Elastomeric Osteoconductive Synthetic Scaffolds with Acquired Osteoinductivity Expedite the Repair of Critical Femoral Defects in Rats
نویسندگان
چکیده
منابع مشابه
Elastomeric osteoconductive synthetic scaffolds with acquired osteoinductivity expedite the repair of critical femoral defects in rats.
Regenerative medicine aspires to reduce reliance on or overcome limitations associated with donor tissue-mediated repair. Structural bone allografts are commonly used in orthopedic surgery, with a high percentage of graft failure due to poor tissue integration. This problem is aggravated among elderly, those suffering from metabolic conditions, or those undergoing cancer therapies that compromi...
متن کامل• Repair of Critical Femoral Defects in Rats by an Osteoconductive Synthetic Bone Graft
Filion, T; Li, X; Kreider, JM; Goldstein, SA; Ayers, DC; +Song, J University of Massachusetts Medical School, Worcester, MA; University of Michigan, Ann Arbor, MI +Senior author [email protected]; Filion and Li contributed equally INTRODUCTION: There is a pressing need for the development of more effective strategies to repair critical-sized bony defects in patients who have had volumetric ...
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Treatment of large segmental bone defects remains an unsolved clinical challenge, despite a wide array of existing bone graft materials. This project was designed to rapidly assess and compare promising biodegradable osteoconductive scaffolds for use in the systematic development of new bone regeneration methodologies that combine scaffolds, sources of osteogenic cells, and bioactive scaffold m...
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ژورنال
عنوان ژورنال: Tissue Engineering Part A
سال: 2011
ISSN: 1937-3341,1937-335X
DOI: 10.1089/ten.tea.2010.0274